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Assay Detail

CHEMBL5332222

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 24 hrs by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Bisindole natural products: A vital source for the development of new anticancer drugs.
Xu M, Peng R, Min Q, Hui S, Chen X, Yang G, Qin S.
Eur J Med Chem (2022) 243 : 114748 -114748
PubMed 36170798 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5418806 1 5.70
CHEMBL1979029 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5418806 IC50 = 2000.0 nM 5.70
CHEMBL1979029 IC50 = 2000.0 nM 5.70