Assay Detail
Binding
CHEMBL5332382
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human beta-Catenin (138 to 686 residues)/C-terminal fluorescein-labeled human APC (1477 to 1519 residues) protein-protein interaction assessed as inhibition constant incubated for 30 mins by fluorescence polarization assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent advances of β-catenin small molecule inhibitors for cancer therapy: Current development and future perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.06 | 4.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3260853 | — | — | 1 | 4.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3260853 | — | Ki | = | 86630.0 | nM | 4.06 |