Assay Detail
Functional
CHEMBL5332765
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Cytotoxicity against human NCI-H460 cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design and synthesis of new adamantyl derivatives as promising antiproliferative agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.05 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 7.30 |
| CHEMBL5432925 | — | — | 1 | 5.64 |
| CHEMBL5404116 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL5432925 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL5404116 | — | IC50 | = | 6100.0 | nM | 5.21 |