Assay Detail
Binding
CHEMBL5332830
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Carbonic anhydrase 2 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by microplate reader method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of new adamantyl derivatives as promising antiproliferative agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.99 | 6.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5404116 | — | — | 1 | 6.06 |
| CHEMBL20 | ACETAZOLAMIDE | 4.0 | 1 | 5.92 |
| CHEMBL265502 | SURAMIN | 3.0 | 1 | - |
| CHEMBL117754 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5404116 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL20 | ACETAZOLAMIDE | IC50 | = | 1190.0 | nM | 5.92 |
| CHEMBL265502 | SURAMIN | IC50 | - | — | - | |
| CHEMBL117754 | — | IC50 | - | — | - |