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Assay Detail

CHEMBL5332968

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Antiproliferative activity against human HET-1A cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type HET-1A
Confidence 1 — Organism
Curated By Autocuration

Target

HET-1A (CHEMBL4296426)
Type CELL-LINE
Organism Homo sapiens

Publication

Novel thiazolidines of potential anti-proliferation properties against esophageal squamous cell carcinoma via ERK pathway.
Aziz MN, Nguyen L, Chang Y, Gout D, Pan Z, Lovely CJ.
Eur J Med Chem (2023) 246 : 114909 -114909
PubMed 36508971 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.89 4.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5405205 1 4.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5405205 IC50 = 13000.0 nM 4.89