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Assay Detail

CHEMBL5333098

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of erastin-induced cell death in human HT-1080 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-1080
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Targeting ferroptosis: Paving new roads for drug design and discovery.
Gu Y, Li Y, Wang J, Zhang L, Zhang J, Wang Y.
Eur J Med Chem (2023) 247 : 115015 -115015
PubMed 36543035 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.62 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3633564 1 8.22
CHEMBL3633556 1 7.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3633564 IC50 = 6.0 nM 8.22
CHEMBL3633556 IC50 = 95.0 nM 7.02