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Assay Detail

CHEMBL5333099

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of ferroptosis in tamoxifen induced Gpx4-/- mouse MEF cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type MEF
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Targeting ferroptosis: Paving new roads for drug design and discovery.
Gu Y, Li Y, Wang J, Zhang L, Zhang J, Wang Y.
Eur J Med Chem (2023) 247 : 115015 -115015
PubMed 36543035 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.66 7.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2094750 1 7.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2094750 IC50 = 22.0 nM 7.66