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Assay Detail

CHEMBL5333291

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at RORgammat (unknown origin) by FRET assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Nuclear receptor ROR-gamma (CHEMBL1741186)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Modes of action insights from the crystallographic structures of retinoic acid receptor-related orphan receptor-γt (RORγt).
Zhang J, Chen B, Zhang C, Sun N, Huang X, Wang W, Fu W.
Eur J Med Chem (2023) 247 : 115039 -115039
PubMed 36566711 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3105815 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3105815 IC50 = 1000.0 nM 6.00