Assay Detail
Functional
CHEMBL5334345
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplasmodial activity against Plasmodium falciparum NF54 incubated for 48 hrs by lactate dehydrogenase assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Basic Nitrogen (BaN) Is a Key Property of Antimalarial Chemical Space.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.25 | 7.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL294083 | — | — | 1 | 7.21 |
| CHEMBL5421256 | — | — | 1 | 5.28 |
| CHEMBL5410379 | — | — | 1 | - |
| CHEMBL5416054 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL294083 | — | IC50 | = | 62.0 | nM | 7.21 |
| CHEMBL5421256 | — | IC50 | = | 5260.0 | nM | 5.28 |
| CHEMBL5410379 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL5416054 | — | IC50 | > | 1000.0 | nM | - |