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Assay Detail

CHEMBL5334871

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human P2Y14R stably expressed in CHO cells assessed as dissociation constant by Cheng-prusoff equation analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

P2Y purinoceptor 14 (CHEMBL4518)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y<sub>14</sub> Receptor Antagonists.
Wen Z, Pramanik A, Lewicki SA, Jung YH, Gao ZG, Randle JCR, Cronin C, Chen Z, Giancotti LA, Whitehead GS, Liang BT, Breton S, Salvemini D, Cook DN, Jacobson KA.
J Med Chem (2023) 66 : 9076 -9094
PubMed 37382926 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.56 7.56

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4447162 1 7.56

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4447162 Kd = 27.8 nM 7.56