Assay Detail
Functional
CHEMBL5335043
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against DENV-3 H87 infected in african green monkey Vero cells incubated for 24 hrs measured after 3 days post infection
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 3 |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.79 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5408964 | — | — | 1 | 7.58 |
| CHEMBL5415953 | — | — | 1 | 7.20 |
| CHEMBL5400299 | — | — | 1 | 6.38 |
| CHEMBL4203293 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5408964 | — | EC50 | = | 26.0 | nM | 7.58 |
| CHEMBL5415953 | — | EC50 | = | 63.0 | nM | 7.20 |
| CHEMBL5400299 | — | EC50 | = | 420.0 | nM | 6.38 |
| CHEMBL4203293 | — | EC50 | = | 1000.0 | nM | 6.00 |