Assay Detail
Binding
CHEMBL5336017
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of purified human PLK (unknown origin) assessed as ATP production by Kinase-Glo Max luminescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Liver cells |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.92 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5429790 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5429790 | — | IC50 | = | 120.0 | nM | 6.92 |