Assay Detail
Toxicity
CHEMBL5336066
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Cytotoxicity against green monkey Vero 76 cells incubated for 48 to 96 hrs by crystal violet staining assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero 76 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.91 | 4.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3352860 | — | — | 1 | 4.91 |
| CHEMBL5286183 | — | — | 1 | 4.91 |
| CHEMBL279014 | LUCANTHONE | 2.0 | 1 | 4.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3352860 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL5286183 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL279014 | LUCANTHONE | IC50 | = | 12400.0 | nM | 4.91 |