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Assay Detail

CHEMBL5336281

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HIV-1 reverse transcriptase associated RNA-dependent DNA polymerase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 1
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Human immunodeficiency virus type 1 reverse transcriptase (CHEMBL247)
Type SINGLE PROTEIN
Organism Human immunodeficiency virus 1

Publication

Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China.
Yang L, Wang Z.
Eur J Med Chem (2023) 257 : 115503 -115503
PubMed 37229831 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.98 5.98

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL438605 1 5.98

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL438605 IC50 = 1050.0 nM 5.98