Assay Detail
Functional
CHEMBL5336308
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against SARS-CoV-2 Omicron assessed as reduction of viral growth
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 7.50 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5404334 | — | — | 1 | 7.62 |
| CHEMBL4802135 | NIRMATRELVIR | 4.0 | 1 | 7.48 |
| CHEMBL4796938 | — | — | 1 | 7.48 |
| CHEMBL5174111 | — | — | 1 | 7.48 |
| CHEMBL5423923 | — | — | 1 | 7.48 |
| CHEMBL5076204 | — | — | 1 | 7.48 |
| CHEMBL5267069 | — | — | 1 | 7.48 |
| CHEMBL5173274 | — | — | 1 | 7.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5404334 | — | EC50 | = | 24.0 | nM | 7.62 |
| CHEMBL4802135 | NIRMATRELVIR | EC50 | = | 33.0 | nM | 7.48 |
| CHEMBL4796938 | — | EC50 | = | 33.0 | nM | 7.48 |
| CHEMBL5174111 | — | EC50 | = | 33.0 | nM | 7.48 |
| CHEMBL5423923 | — | EC50 | = | 33.0 | nM | 7.48 |
| CHEMBL5076204 | — | EC50 | = | 33.0 | nM | 7.48 |
| CHEMBL5267069 | — | EC50 | = | 33.0 | nM | 7.48 |
| CHEMBL5173274 | — | EC50 | = | 33.0 | nM | 7.48 |