Assay Detail
Functional
CHEMBL5336318
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against luciferase-expressing pseudovirus encoding SARS-CoV-2 Omicron expressing S protein infected in human 293T/ACE2 cells assessed as reduction of viral growth measured after 48 hrs by luciferase assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.46 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL451930 | PLITIDEPSIN | 4.0 | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL451930 | PLITIDEPSIN | EC50 | = | 350.0 | nM | 6.46 |