Assay Detail

CHEMBL5336319

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiviral activity against SARS-CoV-2 infected in human A549-ACE2 cells

ChEMBL ↗

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Target

SARS-CoV-2 (CHEMBL4303835) ↗

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Primary target SARS-CoV-2

CHEMBL4303835

Anchored from Assay target.

Protein identity SARS-CoV-2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Severe acute respiratory syndrome coronavirus 2
Confidence	1 — Organism
Curated By	Autocuration

Target

SARS-CoV-2 (CHEMBL4303835) ↗

Type	ORGANISM
Organism	Severe acute respiratory syndrome coronavirus 2

Publication

Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China.

Yang L, Wang Z.
Eur J Med Chem (2023) 257 : 115503 -115503
PubMed 37229831 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.62	6.62

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL449782	CEPHARANTHINE	2.0	1	6.62

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL449782	CEPHARANTHINE	IC50	=	240.0	nM	6.62