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Assay Detail

CHEMBL5336329

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-CoV-2 B.1 infected in Green monkey VeroE6/TMPRSS2 cells assessed as inhibition of viral replication incubated for 2 days by qRT-PCR analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China.
Yang L, Wang Z.
Eur J Med Chem (2023) 257 : 115503 -115503
PubMed 37229831 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.72 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL449782 CEPHARANTHINE 2.0 1 5.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL449782 CEPHARANTHINE IC50 = 1900.0 nM 5.72