Assay Detail

CHEMBL5336366

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Functional

Antiviral activity against SARS-CoV-2 infected in human Calu-3 cells assessed as reduction in viral growth

ChEMBL ↗

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Target

SARS-CoV-2 (CHEMBL4303835) ↗

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Primary target SARS-CoV-2

CHEMBL4303835

Anchored from Assay target.

Protein identity SARS-CoV-2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Severe acute respiratory syndrome coronavirus 2
Confidence	1 — Organism
Curated By	Autocuration

Target

SARS-CoV-2 (CHEMBL4303835) ↗

Type	ORGANISM
Organism	Severe acute respiratory syndrome coronavirus 2

Publication

The research progress of SARS-CoV-2 main protease inhibitors from 2020 to 2022.

Pang X, Xu W, Liu Y, Li H, Chen L.
Eur J Med Chem (2023) 257 : 115491 -115491
PubMed 37244162 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	6.08	6.08

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL5092396	—	—	1	6.08

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL5092396	—	EC50	=	840.0	nM	6.08