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Assay Detail

CHEMBL5336622

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Functional
Antiproliferative activity against human U-937 cells assessed as cell growth inhibition measured after 72 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type U-937
Confidence 1 — Organism
Curated By Autocuration

Target

U-937 (CHEMBL612794)
Type CELL-LINE
Organism Homo sapiens

Publication

Tea-break with epigallocatechin gallate derivatives - Powerful polyphenols of great potential for medicine.
Bakun P, Mlynarczyk DT, Koczorowski T, Cerbin-Koczorowska M, Piwowarczyk L, Kolasiński E, Stawny M, Kuźmińska J, Jelińska A, Goslinski T.
Eur J Med Chem (2023) 261 : 115820 -115820
PubMed 37776575 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.93 5.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2170856 1 5.77
CHEMBL44441 1 4.60
CHEMBL3347644 1 4.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2170856 IC50 = 1700.0 nM 5.77
CHEMBL44441 IC50 = 25000.0 nM 4.60
CHEMBL3347644 IC50 = 37000.0 nM 4.43