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Assay Detail

CHEMBL5337401

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to MT1 receptor (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

2-Phenylcyclopropylmethylamine (PCPMA) as a privileged scaffold for central nervous system drug design.
Li H, Cheng J.
Bioorg Med Chem Lett (2024) 101 : 129654 -129654
PubMed 38360418 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.52 9.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2103822 TASIMELTEON 4.0 1 9.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2103822 TASIMELTEON Ki = 0.3 nM 9.52