Assay Detail
Functional
CHEMBL5337413
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Partial agonist activity at D2R (unknown origin) expressed in HEK293 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
2-Phenylcyclopropylmethylamine (PCPMA) as a privileged scaffold for central nervous system drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.75 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4852835 | — | — | 1 | 8.80 |
| CHEMBL4867794 | — | — | 1 | 8.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4852835 | — | EC50 | = | 1.6 | nM | 8.80 |
| CHEMBL4867794 | — | EC50 | = | 2.03 | nM | 8.69 |