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Assay Detail

CHEMBL5337600

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Influenza A virus A/Aichi/2/68 (H3N2) infected in dog MDCK cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

Discovery of an ellipticine derivative as TLR3 inhibitor against influenza A virus and SARS-CoV-2.
Pan Y, Fu Q, Li Y, Yang J, Cheng K.
Bioorg Med Chem Lett (2024) 101 : 129672 -129672
PubMed 38387691 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL19954 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL19954 IC50 = 250.0 nM 6.60