Assay Detail

CHEMBL5337617

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Functional

Antiviral activity against SARS-CoV-2 infected in African green monkey Vero E6 cells

ChEMBL ↗

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Target

SARS-CoV-2 (CHEMBL4303835) ↗

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Primary target SARS-CoV-2

CHEMBL4303835

Anchored from Assay target.

Protein identity SARS-CoV-2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Severe acute respiratory syndrome coronavirus 2
Cell Type	Vero E6
Confidence	1 — Organism
Curated By	Autocuration

Target

SARS-CoV-2 (CHEMBL4303835) ↗

Type	ORGANISM
Organism	Severe acute respiratory syndrome coronavirus 2

Publication

Discovery of an ellipticine derivative as TLR3 inhibitor against influenza A virus and SARS-CoV-2.

Pan Y, Fu Q, Li Y, Yang J, Cheng K.
Bioorg Med Chem Lett (2024) 101 : 129672 -129672
PubMed 38387691 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.37	6.37

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL19954	—	—	1	6.37

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL19954	—	IC50	=	430.0	nM	6.37