Assay Detail

CHEMBL5337666

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Functional

Antiviral activity against SARS-CoV-2 infected in African green monkey cells assessed as reduction in viral replication

ChEMBL ↗

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Target

SARS-CoV-2 (CHEMBL4303835) ↗

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Primary target SARS-CoV-2

CHEMBL4303835

Anchored from Assay target.

Protein identity SARS-CoV-2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Severe acute respiratory syndrome coronavirus 2
Confidence	1 — Organism
Curated By	Autocuration

Target

SARS-CoV-2 (CHEMBL4303835) ↗

Type	ORGANISM
Organism	Severe acute respiratory syndrome coronavirus 2

Publication

Antiviral Protein-Protein Interaction Inhibitors.

Marković V, Szczepańska A, Berlicki Ł.
J Med Chem (2024) 67 : 3205 -3231
PubMed 38394369 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	5.39	5.39

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1214598	UMIFENOVIR	3.0	1	5.39

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1214598	UMIFENOVIR	EC50	=	4110.0	nM	5.39