Assay Detail
Functional
CHEMBL5338529
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplasmodial activity against immature stage gametocytes Plasmodium falciparum NF54 incubated for 48 hrs by luciferase activity assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
hERG, <i>Plasmodium</i> Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.92 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405110 | METHYLENE BLUE ANHYDROUS | 4.0 | 1 | 6.85 |
| CHEMBL5434807 | — | — | 1 | 5.91 |
| CHEMBL5273140 | — | — | 1 | 5.82 |
| CHEMBL5434251 | — | — | 1 | 5.79 |
| CHEMBL5410878 | — | — | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405110 | METHYLENE BLUE ANHYDROUS | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL5434807 | — | IC50 | = | 1240.0 | nM | 5.91 |
| CHEMBL5273140 | — | IC50 | = | 1520.0 | nM | 5.82 |
| CHEMBL5434251 | — | IC50 | = | 1620.0 | nM | 5.79 |
| CHEMBL5410878 | — | IC50 | = | 5850.0 | nM | 5.23 |