Assay Detail
Functional
CHEMBL5338530
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Antiplasmodial activity against late stage gametocytes Plasmodium falciparum NF54 incubated for 48 hrs by luciferase activity assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
hERG, <i>Plasmodium</i> Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.64 | 5.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5434807 | — | — | 1 | 5.86 |
| CHEMBL5410878 | — | — | 1 | 5.73 |
| CHEMBL5434251 | — | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5434807 | — | IC50 | = | 1390.0 | nM | 5.86 |
| CHEMBL5410878 | — | IC50 | = | 1880.0 | nM | 5.73 |
| CHEMBL5434251 | — | IC50 | = | 4620.0 | nM | 5.33 |