Assay Detail
Functional
CHEMBL5339911
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anti-necroptotic activity in human U-937 cells assessed as inhibition of LPS/Z-VAD-fmk induced necroptosis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-937 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
From (Tool)Bench to Bedside: The Potential of Necroptosis Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.47 | 9.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5173634 | — | — | 1 | 9.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5173634 | — | IC50 | = | 0.34 | nM | 9.47 |