Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5340224

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Anticancer Activity of Region B Capsaicin Analogs.
Brown KC, Modi KJ, Light RS, Cox AJ, Long TE, Gadepalli RS, Rimoldi JM, Miles SL, Rankin G, Valentovic M, Denning KL, Tirona MT, Finch PT, Hess JA, Dasgupta P.
J Med Chem (2023) 66 : 4294 -4323
PubMed 37000154 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.50 4.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4758090 1 4.50
CHEMBL294199 CAPSAICIN 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4758090 IC50 = 32000.0 nM 4.50
CHEMBL294199 CAPSAICIN IC50 ~ 53000.0 nM -