Assay Detail
Binding
CHEMBL5340595
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human trypsin
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Factor XIa Inhibitors in Anticoagulation Therapy: Recent Advances and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.30 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL71037 | — | — | 1 | 7.30 |
| CHEMBL5314583 | FRUNEXIAN | 2.0 | 1 | - |
| CHEMBL5415411 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL71037 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL5314583 | FRUNEXIAN | IC50 | > | 4800.0 | nM | - |
| CHEMBL5415411 | — | IC50 | > | 40000.0 | nM | - |