Assay Detail
Functional
CHEMBL5342771
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human T24 cells assessed as reduction in cell proliferation incubated for 72 hrs by Cell Titer Glo assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T-24 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure-Based Development of Isoform-Selective Inhibitors of Casein Kinase 1ε vs Casein Kinase 1δ.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.23 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4211454 | — | — | 1 | 8.10 |
| CHEMBL5428835 | — | — | 1 | 7.02 |
| CHEMBL5424568 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4211454 | — | EC50 | = | 8.0 | nM | 8.10 |
| CHEMBL5428835 | — | EC50 | = | 95.0 | nM | 7.02 |
| CHEMBL5424568 | — | EC50 | = | 265.0 | nM | 6.58 |