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Assay Detail

CHEMBL5343145

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human 16HBE14o- cells assessed as cell viability measured after 48 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type 16HBE14o-
Confidence 1 — Organism
Curated By Autocuration

Target

16HBE14o- (CHEMBL4296395)
Type CELL-LINE
Organism Homo sapiens

Publication

Novel Triazoles with Potent and Broad-Spectrum Antifungal Activity In Vitro and In Vivo.
Zhu P, Zhou T, Chen H, Chen X, Wang X, Kong L, Yang M.
J Med Chem (2023) 66 : 7497 -7515
PubMed 37218609 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.86 4.86

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5418057 1 4.86
CHEMBL5402275 1 4.86
CHEMBL5420576 1 4.86

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5418057 IC50 = 13970.0 nM 4.86
CHEMBL5402275 IC50 = 13970.0 nM 4.86
CHEMBL5420576 IC50 = 13970.0 nM 4.86