Assay Detail
Binding
CHEMBL5343385
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK2/cyclin A (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel Medicinal Chemistry Strategies Targeting CDK5 for Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.18 | 7.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5430024 | — | — | 1 | 7.20 |
| CHEMBL5093012 | — | — | 1 | 6.35 |
| CHEMBL327004 | — | — | 1 | 5.00 |
| CHEMBL119530 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5430024 | — | IC50 | = | 63.0 | nM | 7.20 |
| CHEMBL5093012 | — | IC50 | = | 444.0 | nM | 6.35 |
| CHEMBL327004 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL119530 | — | IC50 | > | 100000.0 | nM | - |