Assay Detail
Functional
CHEMBL5345225
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Antimalarial activity against Plasmodium falciparum Dd2 assessed as reduction in parasitic growth
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent developments in antimalarial activities of 4-aminoquinoline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.22 | 7.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5438199 | — | — | 1 | 7.84 |
| CHEMBL5431249 | — | — | 1 | 7.73 |
| CHEMBL4098670 | — | — | 1 | 7.15 |
| CHEMBL4215123 | — | — | 1 | 7.13 |
| CHEMBL4098998 | — | — | 1 | 6.76 |
| CHEMBL4208533 | — | — | 1 | 6.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5438199 | — | IC50 | = | 14.43 | nM | 7.84 |
| CHEMBL5431249 | — | IC50 | = | 18.57 | nM | 7.73 |
| CHEMBL4098670 | — | IC50 | = | 71.52 | nM | 7.15 |
| CHEMBL4215123 | — | IC50 | = | 73.35 | nM | 7.13 |
| CHEMBL4098998 | — | IC50 | = | 174.12 | nM | 6.76 |
| CHEMBL4208533 | — | IC50 | = | 186.79 | nM | 6.73 |