Assay Detail
Functional
CHEMBL5345227
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Antimalarial activity against multi-drug resistant Plasmodium falciparum K1 assessed as reduction in parasite growth incubated for 48 hrs by SYBR green assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent developments in antimalarial activities of 4-aminoquinoline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.78 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5399583 | — | — | 1 | 7.30 |
| CHEMBL99254 | — | — | 1 | 6.66 |
| CHEMBL5427728 | — | — | 1 | 6.39 |
| CHEMBL5407217 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5399583 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL99254 | — | IC50 | = | 218.0 | nM | 6.66 |
| CHEMBL5427728 | — | IC50 | = | 405.0 | nM | 6.39 |
| CHEMBL5407217 | — | IC50 | > | 10000.0 | nM | - |