Assay Detail
Functional
CHEMBL5345244
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Antimalarial activity against Plasmodium berghei ANKA
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium berghei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent developments in antimalarial activities of 4-aminoquinoline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.30 | 6.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5394575 | — | — | 1 | 6.41 |
| CHEMBL5414513 | — | — | 1 | 6.32 |
| CHEMBL5408462 | — | — | 1 | 6.31 |
| CHEMBL5422482 | — | — | 1 | 6.23 |
| CHEMBL5430808 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5394575 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL5414513 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL5408462 | — | IC50 | = | 490.0 | nM | 6.31 |
| CHEMBL5422482 | — | IC50 | = | 590.0 | nM | 6.23 |
| CHEMBL5430808 | — | IC50 | = | 600.0 | nM | 6.22 |