Assay Detail
Binding
CHEMBL5346618
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of COX2 (unknown origin) fluorescence based analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Indole-containing pharmaceuticals: targets, pharmacological activities, and SAR studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.16 | 8.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1316 | CARPROFEN | 4.0 | 1 | 8.28 |
| CHEMBL622 | ETODOLAC | 4.0 | 1 | 8.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1316 | CARPROFEN | IC50 | = | 5.3 | nM | 8.28 |
| CHEMBL622 | ETODOLAC | IC50 | = | 9.4 | nM | 8.03 |