Assay Detail
Functional
CHEMBL5347142
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Reversal of ABCB1 mediated doxorubicin-resistance in mouse P388/ADR cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388/ADR |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cancer multidrug-resistance reversal by ABCB1 inhibition: A recent update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.52 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285855 | FANTOFARONE | 2.0 | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285855 | FANTOFARONE | IC50 | = | 30000.0 | nM | 4.52 |