Assay Detail

CHEMBL5347395

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Binding

Inhibition of P13Kgamma (unknown origin) assessed as inhibition constant

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Recent advances in PI3K/PKB/mTOR inhibitors as new anticancer agents.

Occhiuzzi MA, Lico G, Ioele G, De Luca M, Garofalo A, Grande F.
Eur J Med Chem (2023) 246 : 114971 -114971
PubMed 36462440 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	10.70	10.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1236962	OMIPALISIB	2.0	1	10.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1236962	OMIPALISIB	Ki	=	0.02	nM	10.70