Assay Detail
Functional
CHEMBL5348071
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HCV assessed as reduction in viral growth
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Insight into non-nucleoside triazole-based systems as viral polymerases inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 7.32 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL230744 | — | — | 1 | 7.82 |
| CHEMBL509746 | — | — | 1 | 7.80 |
| CHEMBL490672 | FILIBUVIR | 3.0 | 1 | 7.39 |
| CHEMBL516051 | — | — | 1 | 7.23 |
| CHEMBL490671 | — | — | 1 | 7.17 |
| CHEMBL489295 | — | — | 1 | 6.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL230744 | — | EC50 | = | 15.0 | nM | 7.82 |
| CHEMBL509746 | — | EC50 | = | 16.0 | nM | 7.80 |
| CHEMBL490672 | FILIBUVIR | EC50 | = | 41.0 | nM | 7.39 |
| CHEMBL516051 | — | EC50 | = | 59.0 | nM | 7.23 |
| CHEMBL490671 | — | EC50 | = | 67.0 | nM | 7.17 |
| CHEMBL489295 | — | EC50 | = | 310.0 | nM | 6.51 |