Assay Detail
Functional
CHEMBL5348148
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Antiviral activity against HBV infected in human HepG2.2.15 cells assessed as reduction in HBsAg measured after 7 day by enzyme immunoassay relative to control
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Cell Type | HepG2.2.15 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Overview of the development of HBV small molecule inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.27 | 4.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL249448 | — | — | 1 | 4.50 |
| CHEMBL249447 | — | — | 1 | 4.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL249448 | — | EC50 | = | 31900.0 | nM | 4.50 |
| CHEMBL249447 | — | EC50 | = | 90500.0 | nM | 4.04 |