Assay Detail

CHEMBL5348334

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Functional

Antiviral activity against SARS-CoV-2 assessed as inhibition of viral replication

ChEMBL ↗

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Target

SARS-CoV-2 (CHEMBL4303835) ↗

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Primary target SARS-CoV-2

CHEMBL4303835

Anchored from Assay target.

Protein identity SARS-CoV-2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Severe acute respiratory syndrome coronavirus 2
Confidence	1 — Organism
Curated By	Autocuration

Target

SARS-CoV-2 (CHEMBL4303835) ↗

Type	ORGANISM
Organism	Severe acute respiratory syndrome coronavirus 2

Publication

Development of indolealkylamine derivatives as potential multi-target agents for COVID-19 treatment.

Chauhan J, Cecon E, Labani N, Gbahou F, Real F, Bomsel M, Dubey KD, Das R, Dam J, Jockers R, Sen S.
Eur J Med Chem (2023) 249 : 115152 -115152
PubMed 36724633 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.55	5.55

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL490820	—	—	1	5.55

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL490820	—	IC50	=	2800.0	nM	5.55