Assay Detail
Binding
CHEMBL5348486
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant 5-LOX (unknown origin) using H2DCFDA as substrate by measuring fluorescent 2',7'-dichlorofluorescein incubated for 35 mins by plate reader analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Polyunsaturated fatty acid 5-lipoxygenase (CHEMBL215) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Treatment of allergy: Overview of synthetic anti-allergy small molecules in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.64 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4463974 | — | — | 1 | 6.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4463974 | — | IC50 | = | 229.0 | nM | 6.64 |