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Assay Detail

CHEMBL5348487

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of 5-LO (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Polyunsaturated fatty acid 5-lipoxygenase (CHEMBL215)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Treatment of allergy: Overview of synthetic anti-allergy small molecules in medicinal chemistry.
Zhang S, Liu Y, Javeed A, Jian C, Sun J, Wu S, Han B.
Eur J Med Chem (2023) 249 : 115151 -115151
PubMed 36731273 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.54 7.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3416359 1 7.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3416359 IC50 = 29.0 nM 7.54