Assay Detail
Functional
CHEMBL5349952
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Antiviral activity against Variola virus 7124 infected in monkey LLC-MK2 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Variola virus |
| Cell Type | LLC-MK2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.94 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL63647 | — | — | 1 | 7.52 |
| CHEMBL8771 | NEOPLANOCIN A | — | 1 | 7.00 |
| CHEMBL2367975 | — | — | 1 | 6.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL63647 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL8771 | NEOPLANOCIN A | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL2367975 | — | EC50 | = | 510.0 | nM | 6.29 |