Assay Detail
Binding
CHEMBL5350059
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of LPS-induced NFkappaB activation in mouse RAW264.7 cells assessed as effect on LPS-induced nuclear translocation of NF-kappaB incubated for 1 hr
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Bis-chalcones: A review of synthetic methodologies and anti-inflammatory effects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.35 | 5.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL574646 | — | — | 1 | 5.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL574646 | — | IC50 | = | 4500.0 | nM | 5.35 |