Assay Detail
Binding
CHEMBL5350074
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant GLS1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glutaminase kidney isoform, mitochondrial (CHEMBL2146302) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting glutaminase 1 (GLS1) by small molecules for anticancer therapeutics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.70 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3639788 | TELAGLENASTAT | 2.0 | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3639788 | TELAGLENASTAT | IC50 | = | 20.0 | nM | 7.70 |