Assay Detail
Functional
CHEMBL5350356
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human Z138 cells assessed as cell growth inhibition measured after 7 days by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Z-138 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting Arginine Methyltransferase PRMT5 for Cancer Therapy: Updated Progress and Novel Strategies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.66 | 8.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5398215 | — | — | 1 | 8.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5398215 | — | IC50 | = | 2.2 | nM | 8.66 |