Assay Detail
Functional
CHEMBL5350360
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anti-proliferative activity against human Z138 cells assessed as cell growth inhibition incubated for 8 days by Cell-Titer Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Z-138 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting Arginine Methyltransferase PRMT5 for Cancer Therapy: Updated Progress and Novel Strategies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.52 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5422317 | — | — | 1 | 9.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5422317 | — | IC50 | = | 0.3 | nM | 9.52 |