Assay Detail
Functional
CHEMBL5350809
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of citrate uptake expressed in HEK293T
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Opportunities and Challenges for Inhibitors Targeting Citrate Transport and Metabolism in Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.25 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3769578 | — | — | 1 | 6.39 |
| CHEMBL3769514 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3769578 | — | IC50 | = | 410.0 | nM | 6.39 |
| CHEMBL3769514 | — | IC50 | = | 800.0 | nM | 6.10 |